1.利用离子束构建的突变体探讨青霉 YTY 解磷机理的研究， 国家自然科学基金 2014.01-2016.12 30万，主持

2.高酒精度耐受啤酒酵母突变体耐乙醇机理的分析及应用，河南省科技攻关，2022.01 -2023.12 10万，主持

3.高效固态青霉解磷菌肥的制备及生产应用 河南省科技攻关 2019.01 -2020.12，支持

4.木薯精酿啤酒工艺的研发，海南省热带微生物资源重点实验室开放课题，2021.01-2022.12 3万 ，主持

5.河南科技学院科技扶贫项目 商水县精酿酒业科技扶贫专项 2019.03-2020.12 5万，主持

一、科研成果奖

1.河南省科技厅科技进步二等奖，D-核糖发酵工艺研究” ，参与，2008年

2.河南省科技厅科技进步二等奖，作物种子萌发和生长调控物质的开发研究与应用，参与，2012年

3.河南省教育厅科技进步二等奖，鸟苷高产菌株选育及发酵监测工艺优化，主持，2018年

4.河南省教育厅科技成果奖优秀科技论文一等奖，主持，2024年

二、发明专利

1.一种原花青素保健啤酒的生产方法，发明专利，2019，第一

2.鸟苷发酵过程红外指纹图谱的构建方法 ，发明专利，2017，第一

3.利用鸟苷发酵液紫外指纹图谱检测鸟苷产量模型的构建方法，发明专利，2017，第一

4.菠萝酒酿造工艺，发明专利，2016，第二

5.一种小麦麸皮处理方法及其在高效制备多酚物质中的应用，发明专利，2019，第三

三、代表性文章

[1] Hu W, Huo X, Ma T, Li Z, Yang T, Yang H, Feng S. Insights into the role of cyclopropane fatty acid synthase (CfaS) from extreme acidophile in bacterial defense against environmental acid stress. Extremophiles. 2024 Nov 16;29(1):1. doi: 10.1007/s00792-024-01368-w. PMID: 39549088.

[2] Wang F, Wang Y, Li L, Yuan C, Zhang F, Zhang W, Yang T. All-solid-state K+ sensing array based on Au@polystyrene nanocomposites. Mikrochim Acta. 2024 Sep 26;191(10):624. doi: 10.1007/s00604-024-06703-8. PMID: 39322798.

[3] Li L, Yuan C, Zhang L, Chu R, Yu Q, Cai J, Yang T, Zhang M. The impact of simultaneous inoculation with Torulaspora delbrueckii and Hanseniaspora uvarum combined with Saccharomyces cerevisiae on chemical and sensory quality of Sauvignon blanc wines. Front Microbiol. 2024 Jul 24;15:1413650. doi: 10.3389/fmicb.2024.1413650. PMID: 39113838; PMCID: PMC11303216.

[4] Xu J, Liu X, Liang P, Yuan H, Yang T. In Situ Preparation of Tannic Acid-Modified Poly(N-isopropylacrylamide) Hydrogel Coatings for Boosting Cell Response. Pharmaceutics. 2024 Apr 13;16(4):538. doi: 10.3390/pharmaceutics16040538. PMID: 38675199; PMCID: PMC11054217.

[5] Yang T, Zhang S, Pan Y, Li X, Liu G, Sun H, Zhang R, Zhang C. Breeding of high-tolerance yeast by adaptive evolution and high-gravity brewing of mutant. J Sci Food Agric. 2024 Jan 30;104(2):686-697. doi: 10.1002/jsfa.12959. Epub 2023 Sep 15. PMID: 37654243.

[6] Wang B, Li G, Li L, Zhang M, Yang T, Xu Z, Qin T. Novel processing strategies to enhance the bioaccessibility and bioavailability of functional components in wheat bran. Crit Rev Food Sci Nutr. 2024;64(10):3044-3058. doi: 10.1080/10408398.2022.2129582. Epub 2022 Oct 3. PMID: 36190261.

[7] Li L, Pan Y, Zhang S, Yang T, Li Z, Wang B, Sun H, Zhang M, Li X. Quorum sensing: cell-to-cell communication in Saccharomyces cerevisiae. Front Microbiol. 2023 Nov 23;14:1250151. doi: 10.3389/fmicb.2023.1250151. PMID: 38075875; PMCID: PMC10701894.

[8] Zhang RX, Wu ZW, Zhang SJ, Wei HM, Hua CW, Li L, Yang TY. Gene cloning and molecular characterization of a thermostable chitosanase from Bacillus cereus TY24. BMC Biotechnol. 2022 Oct 27;22(1):30. doi: 10.1186/s12896-022-00762-6. PMID: 36303174; PMCID: PMC9615241.

[9] Zhang RX, Wu ZW, Cui HY, Chai YN, Hua CW, Wang P, Li L, Yang TY. Production of surfactant-stable keratinase from Bacillus cereus YQ15 and its application as detergent additive. BMC Biotechnol. 2022 Sep 8;22(1):26. doi: 10.1186/s12896-022-00757-3. PMID: 36076195; PMCID: PMC9454225.

[10] Yang T, Zhang S, Li L, Tian J, Li X, Pan Y. Screening and transcriptomic analysis of the ethanol-tolerant mutant Saccharomyces cerevisiae YN81 for high-gravity brewing. Front Microbiol. 2022 Aug 25;13:976321. doi: 10.3389/fmicb.2022.976321. PMID: 36090078; PMCID: PMC9453260.

[11] Yang T, Li L, Wang B, Tian J, Shi F, Zhang S, Wu Z. Isolation, Mutagenesis, and Organic Acid Secretion of a Highly Efficient Phosphate-Solubilizing Fungus. Front Microbiol. 2022 Apr 25;13:793122. doi: 10.3389/fmicb.2022.793122. PMID: 35547144; PMCID: PMC9082945.

[12] Chen H, Xia Q, Yang T, Bowman D, Shi W. The soil microbial community of turf: linear and nonlinear changes of taxa and N-cycling gene abundances over a century-long turf development. FEMS Microbiol Ecol. 2019 Feb 1;95(2). doi: 10.1093/femsec/fiy224. PMID: 30445630.

[13] Xia Q, Chen H, Yang T, Miller G, Shi W. Defoliation management and grass growth habits modulated the soil microbial community of turfgrass systems. PLoS One. 2019 Jun 24;14(6):e0218967. doi: 10.1371/journal.pone.0218967. PMID: 31233561; PMCID: PMC6590823.

[14] Chen H, Yang T, Xia Q, Bowman D, Williams D, Walker JT, Shi W. The extent and pathways of nitrogen loss in turfgrass systems: Age impacts. Sci Total Environ. 2018 Oct 1;637-638:746-757. doi: 10.1016/j.scitotenv.2018.05.053. Epub 2018 May 11. PMID: 29758430; PMCID: PMC6064208.

[15] Chen H, Xia Q, Yang T, Shi W. Eighteen-Year Farming Management Moderately Shapes the Soil Microbial Community Structure but Promotes Habitat-Specific Taxa. Front Microbiol. 2018 Aug 2;9:1776. doi: 10.3389/fmicb.2018.01776. PMID: 30116234; PMCID: PMC6083213.